what is canagliflozin | how does canagliflozin work
Canagliflozin is an oral antihyperglycemic agent (used to lower blood sugar) that works by inhibiting the sodium-glucose co-transporter 2 (SGLT2). This allows excess glucose to be filtered out of the blood and excreted in the urine.
It is used to control blood sugar in people with type 2 diabetes. It also helps reduce the risk of heart attack and stroke in people with type 2 diabetes and heart disease.
What is canagliflozin?
Canagliflozin is a medicine that lowers blood sugar levels in people with type 2 diabetes. It works by causing the kidneys to get rid of more glucose in the urine. This helps control blood sugar levels and may help prevent serious health problems, including blindness, heart disease, and nerve damage.
This medication comes in tablet form and should be taken by mouth as directed by your doctor. It should be taken at around the same time every day. If you miss a dose, take it as soon as possible and continue with your regular schedule.
Your doctor will also tell you how much of this medicine to take each day. The amount of medicine that you take depends on your medical problem and the other medications you are taking.
how does canagliflozin work?
Canagliflozin works by reducing the amount of glucose in the blood and urine. It does this by blocking an enzyme called SGLT2 that reduces the reabsorption of glucose from the kidney tubules.
In people with type 2 diabetes, this results in a decrease in their blood sugar level. It also helps to lower the amount of fat in their bodies and improve their cholesterol levels.
It is used with diet and exercise to treat adults with type 2 diabetes who are not taking other medications for their disease. It can be taken alone or as an ‘add-on’ to other diabetes medicines, such as metformin.
what is canagliflozin used for
Canagliflozin is used together with diet and exercise to control blood sugar in people with type 2 diabetes. It belongs to a class of medicines called sodium-glucose cotransporter 2 (SGLT2) inhibitors and works by helping the body to remove excess glucose from the blood.
It also increases the amount of water that is filtered out of the blood through the kidneys, which can help reduce high blood pressure. It comes as a tablet to take by mouth and should be taken once a day, usually before breakfast or the first main meal of the day.
where to buy canagliflozin online
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how long does it take for canagliflozin to work
Canagliflozin (Invokana, Novo Nordisk) is an oral diabetes medication that works by increasing the amount of glucose removed from your body by your kidneys. It also makes your urine more acidic, which helps control your blood sugar levels.
The medicine is used to treat type 2 diabetes, a condition in which the body does not produce enough insulin and cannot control the amount of sugar in your blood. It does not cure the disease, but it can help you control your blood sugar and reduce your risk of serious health problems, including heart disease and stroke.
It also lowers your risk of developing kidney disease. It works by blocking a sodium-glucose co-transporter called SGLT2 that normally helps the kidneys get rid of extra sugar in the urine.
To work, canagliflozin should be taken exactly as your doctor prescribes. It comes as tablets to take by mouth, preferably before breakfast or the first main meal of the day.
dosage
Your doctor will start you on a low dose of canagliflozin and gradually increase it to 300 mg daily. This dosage may change if you have kidney problems or if you are taking other medicines.
To get the most benefit from canagliflozin, you should take it at the same time every day, preferably before a meal. It comes as a tablet that you swallow whole with some fluid.
The recommended starting dose is 100 mg taken by mouth once a day. Your doctor might raise the dose to 300 mg daily if you have kidney problems or if it is working well for you.
Precaution
Canagliflozin is used along with a diet and exercise program to treat type 2 diabetes. It also helps lower the risk of heart attack, stroke and kidney disease in people who have diabetes and heart problems.
This medication also helps control high blood pressure. It also increases the amount of potassium in your body, which is needed for normal kidney function. Your doctor may monitor your potassium level to make sure it is not too high or too low.
Your doctor will order regular lab tests to check your blood sugar levels and kidney function while you are taking canagliflozin. They will also check for a condition called ketoacidosis. This is a very serious condition that can be life-threatening. If you get this condition, call your doctor right away.
In 2017, the FDA required a boxed warning about an increased risk of leg and foot amputations with canagliflozin. However, in August 2020 the agency removed this warning based on data from three clinical trials.
